Indocream/Lidocaine Cream (Indomethacin 10/5%)

 

Active Ingredients:

Indomethacin 10, Lidocaine 5%

 

Product(s):

Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. For moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendonitis) and acute gouty arthritis. Anti-inflammatory effects of Indomethacin are believed to be due to inhibition of cylooxygenase in platelets, which leads to the blockage of prostaglandin synthesis. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation.

Lidocaine is a local anesthetic that has neuron membrane stabilizing effect. Topical lidocaine is mostly used in combination with other agents (NSAIDs, muscle relaxants, NMDA-receptor antagonist, and etc…). Lidocaine produces pain relief by blocking the signals at the nerve endings in the skin. Lidocaine causes loss of feeling (numbness) of skin and mucous membranes, which topically is used to relieve pain.

 

How to use your medication:

Apply to intact skin. It is absorbed best after increasing circulation such as after a warm shower or applying a hot compress.

 

Side effects:

Side effects of these medications are not common but when taken orally include: dizziness, fatigue, upset stomach, nausea, vomiting, diarrhea, gas, skin rash, constipation, nervousness, or headache. However, because Indomethacin is used topically, not orally, chances of these side effects, except rash, are very unlikely. If it is bothersome, or if you experience any other side effects not mentioned above, contact your physician or pharmacist. Stop using lidocaine topically and seek medical attention or contact your doctor immediately if you experience any of the following rare but serious side effects: An allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); chest pain or irregular heartbeats, dizziness or drowsiness, nausea and/or vomiting, trembling, shaking, or seizures (convulsions), or blurred or double vision.

 

Precautions:

Do not use this medication if you have had unusual or allergic reactions to the following medications: aspirin, ibuprofen, naproxen, lidocaine, or any other medicine used to treat pain, fever swelling, or arthritis. This medication may add to the effects of depressants or alcohol when taken orally. It is unlikely with a topical form, but discuss with physician or pharmacist if you have questions.

 

Directions:

This medication is for topical use only. Apply the compound to the affected area, in a thin smooth film, 2 to 3 times daily (as needed).  If wearing a brace over the cream, make sure to first air out the area for approximately 30 minutes.  This cream is easily removed with water. The cream should be massaged into the affected area(s) for about 30-60 seconds. Do not use the cream on skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using the cream. Patients should always follow their physician or pharmacist instructions. Patients should not exceed dosage prescribed by their physician.

 

Storage:

This medication should be stored at room temperature away from heat and light.

The information in this handout is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This information is generalized and is not intended as specific medical advice. If you have questions about the medicines you are taking or would like more information, check with your doctor, and/or pharmacist.

 

 

 

The information in this handout is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This information is generalized and is not intended as specific medical advice. If you have questions about the medicines you are taking or would like more information, check with your doctor, and/or pharmacist.